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Antibiotico ciprofloxacino 500 mg /0.5 mL i.p. once a day for 7 days. S. aureus and Escherichia coli isolates were collected by sterile saline swabs. Bacterial growth was examined using an agar plate test kit (Zymotech, Inc., Wilmington, DE, USA) in a 5% CO 2 atmosphere at 37 °C. Results are expressed as counts per liter. The percentage of total CFU per culture is also described as the mean (± SD) and was compared between different treatments. Results show significantly higher levels of bacterial growth in the i.p. than subcutaneous injection group. Figure 7. View largeDownload slide Injection of ciprofloxacin i.v. (Ciprofloxacin, 200 µg i.v.), with or without an antibiotic as a washout (i.w.), significantly increase the caspase 8/36 (BCP/36) ratio in S. epidermidis (A) and Escherichia coli (B) isolates; data are expressed as relative CFU per culture (n = 6–15). Bars represent the mean ± SD for three independent experiments. ∗, P < 0.01; ∗∗, 0.05 relative to i.sub.cutaneous ven